C3nr34124k 1772..1776
نویسندگان
چکیده
Department of Bioengineering, University 92521, USA. E-mail: [email protected] Department of Biomedical Engineering, Wa MO 963130, USA. E-mail: [email protected] Department of Plant Pathology and Microbi Riverside, CA 92521, USA † Authors have no competing nancial in ‡ Electronic supplemental information experimental procedure for fabrication imaging, and immunogenic studies. See D § These authors contributed equally to th Cite this: Nanoscale, 2013, 5, 1772
منابع مشابه
Virus-mimicking nano-constructs as a contrast agent for near infrared photoacoustic imaging.
We report the first proof-of-principle demonstration of photoacoustic imaging using a contrast agent composed of a plant virus protein shell, which encapsulates indocyanine green (ICG), the only FDA-approved near infrared chromophore. These nano-constructs can provide higher photoacoustic signals than blood in tissue phantoms, and display superior photostability compared to non-encapsulated ICG...
متن کاملThe novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes.
The proviral integration site for moloney murine leukemia virus (Pim) kinases, consisting of Pim-1, Pim-2 and Pim-3, belongs to a family of serine/threonine kinases that are involved in controlling cell growth and differentiation. Pim kinases are emerging as important mediators of adipocyte differentiation. SGI-1776, an inhibitor of Pim kinases, is widely used to assess the physiological roles ...
متن کاملPharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.
The serine/threonine family of Pim kinases function as oncogenes and have been implicated in prostate cancer progression, particularly in hormone-refractory prostate disease, as a result of their antiapoptotic function. In this study, we used a pharmacologic inhibitor targeting the Pim family members, SGI-1776, to determine whether modulation of Pim kinase activity could alter prostate cancer c...
متن کاملSGI-1776, an imidazo pyridazine compound, inhibits the proliferation of ovarian cancer cells by inactivating Pim-1.
OBJECTIVE To investigate the antitumor effect of SGI-1776 on human ovarian cancer HO-8910 cells and its molecular mechanism. METHODS HO-8910 cells were cultured in vitro, and the proliferation inhibitory effects of SGI- 1776 were determined by MTT assay and colony formation assay. The effect of SGI-1776 on the distribution of cell cycle phase was observed by flow cytometry with propidium iodi...
متن کاملBlood Chemistries and Body Condition of Steller Sea Lion Pups at Marmot Island, Alaska
thesis. Pages 421-435 in B. Fernholm, K. Bremer and H. Jornvall, eds. The hierarchy of life. Excerpta Medica, Amsterdam. W. E., J. M. V. M. D. M. 1984. Sirenian molecular systematics-including the extinct Stellar’s sea cow (Hydrodamalis gigas). Naturwissenschaften 7 1:586-588. P., T. J. 1989. Three years operational use of satellite telemetry on Florida manatees: tag improvements based on chall...
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تاریخ انتشار 2013